Genotyping for PNPLA3 polymorphisms, the C-allele at rs1010023 (CC and TC genotypes) was associated with hepatic steatosis in CHB patients (odds ratio (OR) = 1.78, 95% confidence interval (CI): 1.05–3.03; P = 0.03) (Table 3). The gene discussed is PNPLA3; the disease is Hepatic steatosis.