HBB and systemic lupus erythematosus: Amino acids 100–119 of Hbα and 100–119 of Hbβ appeared to constitute major auto-antigenic B cell epitopes, since these peptides were preferentially bound by antibodies in the sera of lupus-prone mice (Figure S4A in Supplementary Material); in organ eluates from these mice, several other peptides were also recognized along with these dominant reactivities, but to a lesser extent (Figure S4B in Supplementary Material).