CALR and systemic lupus erythematosus: The second correlate was the higher anti-Hb antibody-secreting B cell precursor frequencies observed in lupus-prone mice, mimicking the higher frequencies of anti-dsDNA, anti-Sm, anti-Ro, and anti-La antibody-secreting B cells seen in lupus in previous studies (28–30), an observation supporting the positioning of Hb as a bona fide autoantigen.