Sheng et al. (2014) reported that the upregulated miR-1246 decreased the expression of cell adhesion target genes and hence promotes the cytotoxicity induced by Ebola virus glycoprotein. Similarly, upregulated miR-1246 was found to promote cell death pathway by reducing the expression levels of DLG3 protein during HEV71 infection in human neuroblastoma cells (Xu et al., 2014). The gene discussed is DLG3; the disease is neuroblastoma.