BDNF and schizophrenia: In contrast, one previous RCT of a hatha yoga intervention in patients with schizophrenia found no changes in BDNF or psychometric measures of resilience levels (Ikai et al., 2014), possibly indicating that such interventions are not as efficacious for individuals with severe psychotic illness, or at least might need to be further adjusted in order to better support wellness in this population.