Second, the CT genotype of the NCOA5 rs2903908 polymorphism seemed to predispose the BD patients to develop both genital ulceration and uveitis more frequently (approximately three-fold for genital ulceration and two-fold for uveitis), whereas the TT genotype of NCOA5 rs2903908 polymorphism was found to have protective impacts on developing genital ulceration or uveitis in the patients with BD. This evidence concerns the gene NCOA5 and Behcet disease.