With the aim of evaluating whether gzmA and/or gzmB deficiency influences local bacterial outgrowth and subsequent dissemination, we determined bacterial loads in the PLF, blood, and liver and lung homogenates of WT, gzmA−/−, gzmB−/−, and gzmAxB−/− mice at predefined time points after infection (Figure 3). This evidence concerns the gene GZMA and infection.