To get insight into the influence of gzmA and gzmB deficiency on the local inflammatory response elicited during septic peritonitis, we measured proinflammatory (TNF-α, IFN-γ, and IL-1β, IL-6) and anti-inflammatory (IL-10) cytokines as well as MCP-1 and KC levels in PLF. Here, GZMA is linked to septic peritonitis.