We found that only endothelial GSK3β serine residue 9 phosphorylation and β-catenin stability are induced by NS/P-bEnd cell contact and that both depend on neural MTP. As shown in Fig. 1, GSK3β serine 9 phosphorylation and β-catenin protein are higher in bEnd cells in direct cell-contact co-culture with NS/P cells (Fig. 1A, +NPC; Fig. 1B, +CTRL NPC) than that in bEnd cells cultured without NS/P cells (Fig. 1A and B, No NPC). This evidence concerns the gene GSK3B and nasopharyngeal carcinoma.