The changes in the neurotransmitters of rats exposed to CUMS were found to be significantly hindered by taurine pre-administration in the present study, the effects of which were similar to the clinical antidepressants that enhance the extracelluar 5-HT and the synaptic level of these neurotransmitters in the brain44, indicating that taurine may inhibit all the behavior disorders observed in un-treated rats exposed to CUMS by the directly regulation of these neurotransmitters. The gene discussed is HTR5A; the disease is Atypical behavior.