Since then, there has been growing evidence that GATA3 could serve as a relatively sensitive diagnostic marker for breast carcinomas, parathyroid tumors, trophoblastic tumors, mesonephric adenocarcinomas, paragangliomas and pheochromocytomas etc. [28–31, 38–42]. The gene discussed is GATA3; the disease is hereditary pheochromocytoma-paraganglioma.