Immunohistochemical staining revealed that the tumor cells were positive for p120 (cytoplasmic) and GATA3 (Fig. 2e, f) and negative for estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), E-cadherin, gross cystic disease fluid protein 15 (GCDFP-15) and mammaglobin. This evidence concerns the gene ESR1 and neoplasm.