The major conclusions of our computational model are that 1) stem cell percentages and proliferation rates have a greater effect on tumor growth than CCR5+ percentages and migration rates, 2) treatments that do not eliminate all stem cells cause tumor reduction but the tumors eventually relapse, 3) maraviroc treatment slightly decreases tumor size, but the effect is not as pronounced as the effects of hypoxia or anti-stem cell treatment, 4) hypoxia accelerates tumor growth, 5) 3D finger-like tumor morphologies occur at higher migration and lower proliferation rates. Here, CCR5 is linked to neoplasm.