SLC30A10 and cirrhosis - dystonia - polycythemia - hypermanganesemia syndrome: Taken together, these results suggest that upregulating ATP2C1 and/or restoring the Mn-responsive trafficking of ATP2C1 may be a viable strategy for increasing Mn clearance in cells in which SLC30A10 is dysfunctional, thereby providing new therapeutic options for patients with HMDPC.