We also found ILK knockdown to have the same effect on MUC1-C expression in two other cancer cell lines, including DU-145 prostate cancer and MDA-MB-231 breast cancer cells (Supplementary Figure S1), revealing that the suppressive effect of ILK depletion on MUC1-C expression was not a cell line-specific phenomenon. The gene discussed is ILK; the disease is cancer.