For instance, miR-200b inhibition promotes Rac1 activation and increases the metastatic potential of HBEC cells.21 miR-200b can repress angiogenesis by targeting angiogenic factors and receptors.22 It can inhibit the epithelial to mesenchymal transition (EMT) by inactivating transcription factors in breast cancer.23 miR-200b is associated with the estrogen receptor status of breast cancer cells.24, 25 Few studies have examined the regulation of fucosyltransferase expression by miRNAs. The gene discussed is RAC1; the disease is breast cancer.