For instance, miR-200b inhibition promotes Rac1 activation and increases the metastatic potential of HBEC cells.21 miR-200b can repress angiogenesis by targeting angiogenic factors and receptors.22 It can inhibit the epithelial to mesenchymal transition (EMT) by inactivating transcription factors in breast cancer.23 miR-200b is associated with the estrogen receptor status of breast cancer cells.24, 25 Few studies have examined the regulation of fucosyltransferase expression by miRNAs. Here, ESR1 is linked to breast cancer.