Current methods for breast cancer diagnosis mainly depend on serological (cancer antigen 15-3, carcinoembryonic antigen, tissue polypeptide antigen, tissue polypeptide-specific antigen) and pathological observations.28 However, cancer antigen 15-3 and carcinoembryonic antigen show low positive rates (15%) for the early diagnosis of breast cancer and are not recommended by the American Society of Clinical Oncology and European Society for Medical Oncology. This evidence concerns the gene CEACAM5 and breast carcinoma.