Therefore, we assembled a panel of 16 bladder cancer cell lines: 11 STAG2-positive, three with deleterious STAG2 mutations (UM-UC-3, UM-UC-6 and VM-CUB-3), one in which STAG2 was inactivated by CRISPR/Cas9 (UM-UC-5 STAG2- 505c6) (Figure 3—figure supplement 2), and two with no detectable STAG2 expression (LGWO1 and MGH-U3) (Supplementary file 2) (Balbás-Martínez et al., 2013; Solomon et al., 2013). The gene discussed is STAG2; the disease is urinary bladder carcinoma.