CD19 and in situ carcinoma: Of the B-cell subsets examined (Figure 7), only transitional CD19+CD20+IgD+CD27−CD24hiCD38hi cells were found to significantly differ in frequency between the CIS and HC groups (median (interquartile range) 3.72 (2.18–4.68) and 1.53 (0.87–2.59) percent of CD19+ B cells, respectively, P=0.019).