While ITCs have been shown to exert pleiotropic effects against cancer (Lamy et al., 2011; Veeranki et al., 2015), CETP was shown to affect cancer and healthy cells in a non-selective way by inducing cell death of HepG2 cells and primary mouse hepatocytes by necrosis (Hanschen et al., 2015). This evidence concerns the gene CETP and cancer.