IL6 and peripheral arterial disease: Patients with PAD have elevated plasma levels of C-reactive protein and inflammatory markers such as monocyte chemotactic protein 1, D-Dimer (a fibrin degradation product), interleukin 6 (IL-6), TNFα, soluble VCAM-1 and soluble iCAM-1 are associated with an inferior performance in the 6 min walking test [5, 143–147].