Examples of this are the eye and pancreas TF Pax6 in retinoblastoma and pancreatic cancer69, 70; myogenic MyoD1 in rhabdomyosarcoma71; hematopoietic progenitor TFs MEIS1 and TAL1 in leukemia72, 73; neural crest SOX10 and MITF in melanoma74, 75 or GATA3 in breast cancer76. This evidence concerns the gene TAL1 and retinoblastoma.