FMO5 and endothelial dysfunction: To examine whether ROS are involved in endothelial dysfunction induced by EMPs (Fig. 5C) and palmitate-induced oxidative stress conditions (Fig. 5D) in mouse aorta, the endothelium-dependent relaxant response to ACh in the presence of the mitochondrial antioxidant, mitoQ, or the NADPH oxidase inhibitor, apocynin, were analyzed.