In patients with CAD compared to those without, pre-ischemia left ventricular expression levels of ITLN1 were slightly higher (median 89.64 FPKM interquartile range 4.60–331.00 vs median 43.53 interquartile range 5.62–281.85, p = 0.839) while pre-ischemia plasma levels of ITLN1 were slightly lower (mean 30.94 ± 14.44 ng/ml vs mean 33.56 ± 16.03 ng/ml, p = 0.378) but these associations were not significant. The gene discussed is ITLN1; the disease is ischemia.