These include hemoglobin genes (HBB, HBG1, HBG2) in the peripheral blood-derived cell line KU812, MIA (melanoma inhibitory activity) in the melanoma-derived cell line A375 [21] as well as insulin (Ins1, Ins2) and islet amyloid polypeptide (Iapp) in the mouse pancreatic beta cell line Beta-TC6 (Additional file 7: Figure S7). Here, HBG1 is linked to melanoma.