UCP2 and type 2 diabetes mellitus: Accordingly, LTL in T2DM patients of a diverse ethnic background was found to be positively correlated with plasma total antioxidant status and carriers of a variation (the 866-A allele that is associated with lower UCP2 transcription) in uncoupling protein 2 (UCP2) had shorter age-adjusted LTL than their homozygote counterparts [12].