Several recent studies have demonstrated that systemic inflammatory response (SIR) markers, including C-reactive protein (CRP) [5], Glasgow prognostic score (GPS) [6], platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR) [7], are correlated with poor survival rates of CRC and many other cancers [5, 8]. This evidence concerns the gene CRP and colorectal carcinoma.