Such factors having exclusively been induced by the E. coli infection included several TNFα induced proteins (TNFAIP230; TNFAIP331, also known as ubiquitin-editing enzyme A20; TNFAIP632) the suppressors of cytokine signaling SOCS1, SOCS333 and the NF-κB inhibitors NFKBIA, NFKBID, NFKBIE34. The gene discussed is NFKB1; the disease is escherichia coli infection.