2005). The risk of nocturnal hypoglycemia after HIIE in youth with T1D is poorly understood, but is likely due to HIIE having greater insulin sensitizing effects than MIE (Cockcroft et al. 2015). This is indirectly supported in the present study by an increase in the insulin:CHO ratio in both exercise conditions but not CON, with a larger increase after HIIE. It is also noteworthy that the highest incidence of hypoglycemic events throughout the 24‐h period occurred in participant C, whose HbA1c was the lowest of the participants. The gene discussed is INS; the disease is type 1 diabetes mellitus.