MAPK1 and cancer: Out of genes affected by a somatic small indel in the MSS tumor, six were also listed in the cancer gene census table of the COSMIC database including somatic frameshift indels in BRAF, ZFHX3 (both associated with GC), MAPK1, and ARID1A. BRAF and ARID1A were affected by cross platform indels, while indels in ZFHX3 and MAPK1 were exclusively called and covered in the WGS data.