In the MSI tumor 22 (17 non-overlapping) somatic inversions affecting eight genes were detected: DCK (intronic), SPINK14, AHCYCL2, FAM40B, LOC642236, CCDC88C, LOC440434, and CCDC102B. In the MSS tumor 95 (89 non-overlapping) somatic inversions in 30 genes were identified, of which eight were at least partially located in exonic regions: WARS2, NASP, AKR1A1, RIMS1, EPHA5, GRID1, KCNMA1, and SPINK14. In both patients a somatic inversion affected the gene SPINK14. The gene discussed is SPINK14; the disease is neoplasm.