Moreover, OPG was directly correlated with SBP (p < 0.0001), hypertension duration (p = 0.0018), PTH (p < 0.0001), phosphate (p < 0.0001), CRP (p < 0.0001), and macrovascular events (p < 0.0001). This evidence concerns the gene TNFRSF11B and hypertensive disorder.