MELK and infection: Importantly, more viral cores were found 8 h post-infection in MELK-KD cells than in Non-T cells regardless of proteasome inhibition, indicating that depletion of MELK in MT4C5 cells impaired the dissociation of CA from the HIV-1 core (Fig 2I, panel CA of fraction #3, MG132 [–] and MG132[+], compare Non-T and MELK-KD-2).