We previously reported that fasting glucose levels below 135 mg/dL and changes from pre-breakfast to 1- and 2-hour post-breakfast glucose levels in excess of 54 mg/dL and 78 mg/dL, respectively, may have a 60% to 80% probability of estimating the occurrence of nocturnal asymptomatic hypoglycemia in inpatients with type 1 diabetes receiving insulin detemir or insulin glargine [24]. Here, INS is linked to type 1 diabetes mellitus.