CD274 and neoplasm: Based on a ≥5% PD-L1 expression cutoff assessed prospectively on tumor cells, ORR was significantly higher in PD-L1 positive patients (25.0%; 95% CI, 14.4–38.4) compared with PD-L1 negative subgroup (14.7%; 95% CI, 7.6–24.7; p = 0.178).