DNMT1 and neoplasm: Expression levels of DNA methyltransferases (DNMTs) as DNA methylation factors (DNMT1 and DNMT3a), DNA demethylation factors (TET1, TET2, TET3, AICDA and GCM1) and MUC4 were evaluated in tumors representative of early stage (Tumor size < 10mm), later stages, lymphatic permeation negative and positive samples, and vascular permeation negative and positive samples (summarized in Table S3).