ELN and Intellectual disability: This syndrome is featured by a range of neurodevelopmental and behavioral abnormalities, and additional copies of the two elastin genes responsible for anomalies of connective tissue as well as GTF21 implicated in mental retardation within the intervals are likely to contribute to some of the characteristics observed in 7q11.2 duplication syndrome; however, the exact pathology for this syndrome remains unclear (Kirov et al., 2012; Mulle et al., 2014).