Especially, a high constitutive BAG3 expression is reported in muscle cells (heart and skeletal) and in cells of different cancer types (e.g., lymphoid or myeloid leukemias, neuroblastomas, prostate carcinomas, ovarian and breast carcinomas, glioblastomas or pancreatic carcinomas) (Liao et al., 2001; Homma et al., 2006; Rosati et al., 2007a; Gentilella and Khalili, 2011; Felzen et al., 2015; Sherman and Gabai, 2015). Here, BAG3 is linked to cancer.