BAG3 and myopathy: In Drosophila melanogaster the muscle integrity and muscular protein homeostasis is ensured by an analogous macroautophagy process (called CASA) that is mediated by the functional BAG3 ortholog starvin (see Impact of BAG3 on Myopathies) (Arndt et al., 2010; Ulbricht et al., 2013b).