Other studies on the prevalence of BRCA1/2 mutations in unselected breast cancer patients from Brazil (n = 402), Mexico (n = 810; n = 96), Colombia (Medellin) (n = 244), Cuba (n = 307) and Peru (n = 266) have reported frequencies in the range 0.3–11.4% for BRCA1 and 0.4–3.1% for BRCA2 mutations12, 13, 17, 29–32. This evidence concerns the gene BRCA1 and breast carcinoma.