We also report that the same antibody combinations can be used successfully to attenuate allergic responses (IgE production after immunization of mice with OVA in alum, and production of IL-4 cytokines in these same mice—see Figure 7), and of inhibiting tumor growth and preventing metastases in the EMT6 mouse breast cancer model (Figure 8). The gene discussed is IGHE; the disease is breast carcinoma.