The fact that the experimental total leukemic burden (black triangles) exceeds y(t) (black curve) substantially except for the values at 270d is consistent with PP14 and may reflect unidentified BCR-ABL1 clone(s), e.g., contributions from the wild-type CML strain. The gene discussed is BCR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.