IL10RA and colitis: The IL10R is expressed on cells of both the innate and adaptive immune compartments and a number of studies have highlighted the role of IL10R on subsets of regulatory T cells and T helper 17 (Th17) cells in preventing the development of colitis (Chaudhry et al., 2011; Huber et al., 2011; Kamanaka et al., 2011; Murai et al., 2009).