Many voltage-gated potassium channel α subunits were among the plausible target genes downregulated following nerve injury and predicted as targets of pain-relevant miR-17-92 cluster members (Fig. 4a), including KV1.1, KV1.4 and KV4.3 (refs 21, 22, 23, 24, 25). This evidence concerns the gene KCNA1 and injury.