There were no significant differences in the distribution of the NF-κB1 (rs28362491; −94 ins/del ATTG), TLR2 (rs201786064, −196/−174 del/ins) and TLR4 (rs4986790; Asp299Gly, 13,843 A > G; and rs4986791, Thr399Ile, 14,143 C > T) alleles and genotypes between the groups of RA patients and healthy controls (Table 2). This evidence concerns the gene TLR4 and rheumatoid arthritis.