TLR9 and rheumatoid arthritis: Interestingly, the TLR9 −1486 T allele was more frequently detected among patients with RA than healthy individuals, independently of the sex (OR = 11.118, p < 0.001, Table 3; OR = 18.466 and OR = 6.935 for females and males, respectively, with p < 0.0001 in both cases, Figure 1).