Lundbo and co-workers also found the association of pneumococcal meningitis with the polymorphism of nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor (NFKBIE) and that the increased risk of invasive pneumococcal disease (IPD) was in the heterozygosity meningitis group for NFKBIE (Lundbo et al., 2016). Here, NFKBIE is linked to meningitis.