The P. yoelii rodent malaria parasite orthologs for the CoA biosynthesis enzymes PPCS (PlasmoDB ID: PY17X_0616300), PPCDC (PlasmoDB ID: PY17X_0714900), PPAT (PlasmoDB ID: PY17X_0805100), and DPCK (PlasmoDB ID: PY17X_1311400) are all highly conserved by chromosomal synteny and share considerable amino acid identity with other Plasmodium species orthologs (Figure 1). This evidence concerns the gene COASY and malaria.