However, our results do not automatically imply, that CFP is not involved in degeneration, as we know from other studies that CFP deposition was positive in patient eyes with AMD (Wolf-Schnurrbusch et al., 2009) and was associated with drusen-like deposition in Alzheimer’s disease (Fonseca et al., 2011). This evidence concerns the gene CFP and early-onset autosomal dominant Alzheimer disease.