INS and hydrops fetalis: Body weight (Fig. 1A), glucose (Fig. 1B), insulin (Fig. 2A), and HOMA‐IR (Fig. 2B) in HFEX mice were not different from Std sedentary mice, thus voluntary running wheel exercise prevented deleterious changes in all of these metabolic variables, despite significantly greater daily caloric intake in HFEX (18.4 ± 1.9 kcal/d) compared to Std (12.7 ± 2.5 kcal/d, P < 0.001) and HF (14.0 ± 1.1 kcal/d, P < 0.001).