VEGFA and myocardial infarction: Our finding of unchanged expression of Vegfa in Hsd11b1MKO compared to control mice (also unchanged in global 11β-HSD1-deficient mice in a model of myocardial infarction (McSweeney et al. 2010)) is consistent with 11β-HSD1 acting in tissue-resident macrophages to restrain angiogenesis, downstream of VEGF-α.