In the HD cohort (n = 12), KIR2DL1/DS1, KIR2DL2/DL3/DS2 and KIR3DL1, CD57, NKG2D, SIGLEC-7, CD38, CD244, CD62L, CD8, and CD226 were more expressed on CD56dimCD16bright than on CD56dimCD16− cells, whereas NKG2A, CD27, CD69, and HLA-DR varied in an opposite manner (Figure 3; Figures S1 and S2 in Supplementary Material), suggesting overall a more mature phenotype of CD56dimCD16bright than CD56dimCD16− NK cells. This evidence concerns the gene CD27 and Huntington disease.