Through activation of p53, many herbal extracts, including the extracts of Hibiscus syriacus (Cheng et al., 2008), Bing De Ling (Xu et al., 2005), Suillus collinitus (Vaz et al., 2012), Emilia sonchifolia (Lan et al., 2012), Cochinchina momordica (Liu H.R. et al., 2012), Zeng Sheng Ping (Zhang et al., 2004), and JP-1 (Yao et al., 2016), have been shown to induce growth arrest or metastatic activity of test cancer cells. The gene discussed is TP53; the disease is cancer.