Thus, Bax/Bcl-2 ratio increased in MM cell lines treated with API as compared to cells treated with DMSO (MM-F1, p = 0.017; MM-B1, p = 0.02; H-Meso-1, p = 0.014; #40a, p = 0.018) (Figures 5A,C). The gene discussed is BAX; the disease is Miyoshi myopathy.