Currently, the role of androgens in endometrial cancer is thus not well-defined, although higher blood concentrations of androgens seen in patients with type I endometrial cancer, together with the presence of the androgen receptor and androgen-metabolizing enzymes in tissue samples, have suggested that androgens do not serve only as precursors of estrogens, but probably have discrete roles in the pathophysiology of this gynecological cancer. Here, AR is linked to endometrial cancer.