DNMBP and pulmonary arterial hypertension: PAH-PASMCs exposed to TubA or ACY-775 displayed a dose-dependent increase in the amount of acetylated α-Tubulin18 without affecting the total levels of α-Tubulin and the global degree of histone H3 acetylation, thus confirming the selectively of these inhibitors for HDAC6 (Supplementary Figure S4).